HYDROCEL L-HPC

L-HPC (Low-Substituted Hydroxypropyl Cellulose) was first approved in 1977 as a disintegrant for pharmaceutical dosage forms in Japan. L-HPC is ranked as the first choice of tablet disintegrant by Japanese pharmaceutical companies. It has excellent compatibility with active ingredients. It disintegrates into smaller particles leading to better dissolution & has anti-capping effect for tableting process. With narrow parameter range Hydrocel range of Cellulose & Polymers have gained excellent feedback from the customers and has excellent performance results.

USP/Ph. Eur/BP/IP

Application: Disintegrant
Dosage Form: Solid Orals
Cas No: 9004-64-2

Hydrocel L-HPC | 1
LHPC Super Disintegrant PIOMA Chemicals
LHPC Supplier & Manufacturer
Grade/ variant INCI Name
L-HPC LH 11 Low Substituted Hydrxy Propyl Cellulose LH 11
L-HPC LH-21 Low Substituted Hydrxy Propyl Cellulose LH 21

FAQs – Hydrocel L-HPC

Q1. What is Hydrocel L-HPC?
Hydrocel L-HPC (Low-Substituted Hydroxypropyl Cellulose) is a super disintegrant widely used in solid oral pharmaceutical formulations. It enhances tablet disintegration, improving dissolution and bioavailability of active pharmaceutical ingredients (APIs).

Q2. What are the main applications of Hydrocel L-HPC?
Hydrocel L-HPC is mainly used as a disintegrant in solid oral dosage forms such as tablets and capsules.

Q3. How does Hydrocel L-HPC work in tablets?
It rapidly disintegrates tablets into smaller particles, promoting faster dissolution. Additionally, it prevents tablet defects such as capping and lamination during the manufacturing process.

Q4. Why is Hydrocel L-HPC preferred by pharmaceutical companies?
L-HPC is highly compatible with active ingredients, offers excellent disintegration efficiency, and ensures consistent tablet quality. It is widely recognised as the first-choice disintegrant in Japan.

Q5. What grades of Hydrocel L-HPC are available?

L-HPC LH-11 – Low Substituted Hydroxypropyl Cellulose LH-11

L-HPC LH-21 – Low Substituted Hydroxypropyl Cellulose LH-21

Q6. What pharmacopeia standards does Hydrocel L-HPC comply with?
It complies with USP, Ph. Eur, BP, and IP standards.

Q7. What is the CAS number of Hydrocel L-HPC?
The CAS number is 9004-64-2.

Q8. Who can supply Hydrocel L-HPC?
Hydrocel L-HPC is supplied by PIOMA Chemicals and other trusted manufacturers and suppliers worldwide.